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By Anonymous - / Sunday 21 April 2013 17:36 / Kuwait - Kuwait
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Cryptic17 - No, the thing that will increase is the concentration if the drug in her bloodstream, and when you increase the plasma concentration, you generally increase the response. SapphireVelvet is right - OP IS clueless.

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Umm... OP is clueless, as well as most of the people on this thread. I don't understand why so many people think he's right. There are many factors to it probably won't triple the dosage it'll be close enough. Where's your head people? Hell, Alieve says it on the commercial. "Take 2 pills for a day free of pain". I trust DocBastard, my doctor, and common sense. So thumb me down if you must.

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Cryptic17 - No, the thing that will increase is the concentration if the drug in her bloodstream, and when you increase the plasma concentration, you generally increase the response. SapphireVelvet is right - OP IS clueless.

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It will certainly increase the response, but trying to quantify the exact degree of the drug's effect on a given person is a difficult thing to do. I doubt that the dosage and degree of effect would be linearly proportional.

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Cryptic 17- not all "increased doses" equate to death. For example, a boatload of xanax in a patient not taking other medications would just cause a temporary coma with stable vitals. Another example: there is no.maximum dose of opioid pain medications (it all depends on your tolerance). and, tolerance does not equal addiction. Oyyyy the medical ignorance makes my brain hurt.

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How is this comment thumbed down? Of course will an increased dose of painkillers give more painrelief. Thats the principle we work by when we give them to cancer patients in palliative care etc. As long as she's under the toxic dose, it will increase the effect. If she combined two she may even get a synergetic effect.

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In the Xanax example, I know people who are prescribed a triple dose of what I have. I've had double my painkiller dose prescribed after a surgery. During a mania, I had a med tripled. Safe doses do range.

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Wow. Where to start? Well, op is a clueless. There are a lot of factors that play into how much dosage will effect someone. Even so, the plateau effect dose (the dose where the maximum therapeutic effect can be seen) of most pain killers is much higher than the recommended dose (usually near the threshold dosage (dose where minimum therapeutic effect can be seen). Patient's tolerance to a medication can effect both these levels; they are more so generalized for the mass majority of people. By nature, over the counter pain killers are toxic, but the dose where they become lethal is extremely high. I don't want to go more in depth with this because I have better things to do with my time than argue with people who know nothing about what they are talking about, like op. Trust me, I'm an engineer.

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If a person who never tried opiates (morfine, heroine etc.) takes them, they can overdose (supress the need to breathe while in a coma and therefore suffocate), on far far less than a drugaddict. A drugaddict has far fewer receptors for the drug after using it for a while- and therefore need more to get the effect of it.

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Taking the occasional higher dose of pain killers will not kill you. I've been getting semi-frequent headaches since I was about 11 years old, which led to me having an extremely high tolerance for pain medication. By now, I HAVE to take a higher dose than it says on the bottle because it will not work otherwise. Sure, if you sit there and chew pills like candy for hours on end every day, that's when those side effects will start appearing. But taking higher doses of them every once in a while? No.

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Woah #4, that was intense. Even real drug addicts shouldn't just DIE, they need help! Besides, if drugs weren't a world wide problem, something else would be.

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